The mother of Jesus and his brothers came to him
but were unable to join him because of the crowd.
He was told, "Your mother and your brothers are standing outside
and they wish to see you."
He said to them in reply, "My mother and my brothers
are those who hear the word of God and act on it."
In this passage there are many opinions on the extended family of Jesus. Some scholars have noted that here "brothers" is referring to Jesus cousins since the term brothers can be used to refer to one's extended family. Others note that it is likely referring to Jesus' actual siblings, meaning Mary likely had children after Jesus. Either way, what is important is that Jesus extends the concept of family beyond the biological to the entire people of God. Those who have faith are part of this family. More precisely, those who have faith and use it to user in the Kingdom of God is part of his holy family.